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The Health Benefits of Vitamin E

The role of vitamin E, selenium and folic acid in improving sperm parameters after varicocelectomy: a randomized clinical trial. Ardestani-Zadeh, A., Arab, D., Kia, NS and others Vitamin E health claims are not covered by a significant scientific agreement with the FDA. [Sources: 3]

The effect of vitamin E supplementation on vitamin A status in adults with normal coagulation status. Vitamin E in the treatment of tardive dyskinesia. Brand C, Snaddon J, Bailey M, Cicuttini F. Vitamin E is ineffective for symptomatic relief of knee osteoarthritis after six months: a blind, randomized, placebo-controlled study. Antioxidant dietary supplement and long-term reduction of recurrent adenomas of the colon. [Sources: 3]

The benefits of vitamin E oils for cosmetics are scientifically only limited. Before using vitamin E oil, you should consult a doctor or skin care expert. Vitamin E is not a single vitamin, but a group of fat-soluble vitamins with antioxidant effects. [Sources: 7]

Vitamin E is fat soluble and accumulates throughout the body in the tissues. A high dose of vitamin E can reduce your body’s vitamin reserves. Vitamin E can also enhance the effect of oral blood-thinning drugs such as anticoagulants. This can lead to an increase in blood clots and, over time, bleeding. [Sources: 6]

After topical application, vitamin E not only accumulates on the cell membrane, but also in the extracellular lipid matrix stratum corneum, where it contributes to antioxidant defense. Too much or too much vitamin E can destroy the skin when exposed to UV light. [Sources: 0]

Environmental pollutants such as ozone can reduce the vitamin E level in the skin [6, 11, 12], which can lead to damage by free radicals and increase the effects of UV exposure [12]. Although not well studied, the topical application of vitamin E can reduce environmental damage caused by free radicals [11]. [Sources: 0]

Signs & Symptoms of Vitamin E Deficiency

Vitamin E deficiency affects skin function, but there is little evidence from human studies. It has been reported that vitamin E deficiency in rats causes skin ulcers [22] and changes in the collagen crosslinking of the skin [23, 24], but the underlying causes of these effects are unknown. [Sources: 0]

Overall, observational studies have not shown that vitamin E foods and supplements offer much protection against cancer in general or certain cancers. Cancer The history of vitamin E and cancer prevention is slightly less encouraging than the history of vitamin E and heart disease. [Sources: 8]

Many studies have looked at people with advanced heart disease and Alzheimer’s disease. In some studies vitamin E has been combined with high doses of beta-carotene, which itself is associated with excessive mortality. [Sources: 8]

However, it is not clear whether these findings apply to healthy people. The Physicians Health Study II, for example, found no difference in mortality rates between study participants taking vitamin E and those taking placebo. [Sources: 8]

Kirkpatrick, C. S., White, E., & Lee, J. A. A case-control study on malignant melanoma in Washington State. Karlson, E. W., Shadick, N. A., Cook, N.-R., Buring, J.-E., Lee, I. M. Vitamin E as primary prevention of rheumatoid arthritis: a study on women’s health. [Sources: 3]

Since the amount of vitamin E used in the above-mentioned studies was so high, it is difficult to increase the level of antioxidants in the brain tissue. In fact, researchers have found that even a high intake of vitamin E (e.g. 4,000 IU per day) does not increase vitamin E levels in the brain. The difficulty of increasing vitamin E levels in the brain could explain the poor results in large controlled studies. [Sources: 5]

There is evidence that high-dose vitamin E supplements can increase the risk of prostate cancer. High doses of vitamin E (400 IU or higher) have been associated with shorter lifespan compared to placebo. This may be due to an increased risk of hemorrhagic stroke, which some scientists believe may be linked to vitamin E supplementation. [Sources: 9]

Vitamin E supplementation has been shown in controlled studies to increase walking distance and blood flow to the arteries in the lower legs in people with intermittent cladication. An increased food intake of vitamin E was also associated with better blood circulation in the legs. However, previous studies have not shown that vitamin E is clinically meaningful. [Sources: 5]

Doses of 1,000 mg to 1,500 IU seem safe for most adults. For infants up to the age of 6 months the RDA is 4 mg to 6 IU and between the age of 6 months and one year 5 mg to 7.5 IU. At the age of 1 to 3 years, 4 to 8 years and 9 to 13 years the value of vitamin E according to NIH is 6 mg to 9 IU, 7 mg to 10.4 IU and 11 mg to 16.4 IU. [Sources: 4]

The recommended dietary supplement (RDA) for vitamin E is 15 milligrams (224 international units, or IU) for people under 14, according to the National Institutes of Health (NIH). Breastfeeding women need more vitamin E, so the RDA for breastfeeding women is 19 mg (284 IU). [Sources: 4]

Talk to your doctor about how vitamin E can be used if you are about to have it or if you have a procedure to open a blocked artery and restore normal blood flow to your heart muscle (angioplasty). If you are planning surgery, stop taking vitamin E after two weeks. [Sources: 2]

Most vitamin E in the American diet consists of gamma-tocopherol from soybeans, rapeseed, maize and other vegetable oils and foods (4). Many foods provide vitamin E, but nuts, seeds and vegetable oils are the best sources of alpha-tocopherol, and substantial amounts are also available from leafy green vegetables and fortified cereals (see Table 2 for a detailed list) (9). [Sources: 1]

The serum concentration of vitamin E (alpha-tocopherol) depends on the liver, which absorbs the nutrient in various forms that are absorbed by the small intestine. The liver releases alpha-tocopherol in the liver, where it is transferred to proteins 1, and the liver metabolizes and excretes other forms of vitamin E 2. As a result, the blood and cell concentrations of the other forms are lower than those of alpha-tocopherol, which has been less studied [3,4]. [Sources: 1]

Sources

[0]: https://lpi.oregonstate.edu/mic/health-disease/skin-health/vitamin-E
[1]: https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/
[2]: https://www.mayoclinic.org/drugs-supplements-vitamin-e/art-20364144
[3]: https://www.webmd.com/vitamins/ai/ingredientmono-954/vitamin-e
[4]: https://www.livescience.com/51543-vitamin-e.html
[5]: https://wa.kaiserpermanente.org/kbase/topic.jhtml?docId=hn-2931005
[6]: https://www.urmc.rochester.edu/encyclopedia/content.aspx?contenttypeid=19&contentid=vitamine
[7]: https://www.medicalnewstoday.com/articles/318168
[8]: https://www.hsph.harvard.edu/nutritionsource/vitamin-e/
[9]: https://www.verywellfit.com/vitamin-e-supplements-what-you-need-to-know-90042